Postoperative Adjuvant Therapies and Survival in High-Risk Endometrial Cancer

E11   |  15 min   |   Latest   |  Publication Source   

• Podcast based on: Lee HJ, Lee B. Impacts of Postoperative Adjuvant Therapies on the Survival of Women with High-Risk Early-Stage Endometrial Cancer: A Cohort Study. Cancers. 2025; 17(2):187. https://doi.org/10.3390/cancers17020187
  Type: Article  |  Publication date: Jan 7, 2025
  
  
• Summary: This Korean cohort study investigated the impact of various postoperative adjuvant therapies on the overall survival (OS) of women with high-risk early-stage endometrial cancer. The researchers analysed data from 1341 patients, comparing OS across different treatment groups including radiotherapy, chemotherapy, and hormone therapy. Results indicated that most adjuvant therapies yielded similar OS rates, except for adjuvant radiotherapy after chemotherapy, which showed significantly lower survival. The study also revealed differences in OS based on the type of cancer histology (endometrioid versus non-endometrioid). These findings offer valuable insights for selecting appropriate adjuvant therapies for this patient population, though further research is needed due to limitations in sample size for certain treatments.
  
  
• Keywords: endometrial cancer; adjuvant therapy; radiotherapy; chemotherapy; hormone therapy

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